001Lion's ManeHericium erinaceus1,000 mg

What it is
A culinary and medicinal mushroom with a distinctive white, cascading shape. It is unusual among fungi for containing two families of compounds, hericenones and erinacines, that scientists have studied for their effect on nerve growth factor in the lab.
Why we chose it
Lion's Mane is the most-studied nootropic mushroom and the natural anchor of our mushroom trio. We were drawn to the growing body of human work in older adults, and to the mechanistic NGF research that makes it genuinely interesting to neuroscientists. It is the ingredient people most associate with clear-headed function, so it belongs at a real dose, not a sprinkle.
We use a full 1,000 mg of dual-extracted fruiting body, the part of the mushroom the research uses, not mycelium grown on grain. It anchors the daily mushroom trio in every scoop.
What the research has explored
- Human RCT
Mori et al., 2009, Phytotherapy Research. 3 g/day, 16 weeks, 30 older adults. Cognitive-scale scores rose above placebo through the trial and eased back after stopping. PMID 18844328
- Human RCT
Li et al., 2020, Frontiers in Aging Neuroscience. ~1,050 mg/day erinacine-enriched mycelium, 49 weeks, mild Alzheimer's. Improved memory-scale and daily-living scores. PMID 32581767
- Human RCT
Nagano et al., 2010, Biomedical Research. ~2 g/day, 4 weeks, 30 women. Explored mood; reported lower scores on irritation and anxiety measures vs placebo. PMID 20834180
- Mechanistic
Mori et al., 2008, Biol Pharm Bull. Lab study; Lion's Mane extract stimulated nerve-growth-factor synthesis in human astrocyte cells. PMID 18758067
How we read it: the human trials are real and several are positive, often in older or impaired groups and at varied doses. We describe what they investigated; Lion's Mane has no authorised EU health claim, so we make no cognition or focus claim for the product.


















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